CD69 Antibody [H1.2F3] (APC)
Product Specifications
Background
The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) . It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
NCBI Gene ID
12515
Swiss Prot
P37217
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Clone
H1.2F3
Conjugation
APC
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Armenian Hamster IgG
Specificity
The H1.2F3 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) .
Symbol
Cd69
NCBI Official Name
CD69 antigen
NCBI Organism
Mus musculus
Background Reference 01
Ge, A. Z., Butcher, E. C. (1994) . Cloning and expression of a cDNA encoding mouse endoglin, an endothelial cell TGF--beta- ligand.Gene,138 (1), 201-206.
Background Reference 02
Onoe, T., Ohdan, H., Tokita, D., Shishida, M., Tanaka, Y., Hara, H., ... Asahara, T. (2005) . Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice.The Journal of Immunology,175 (1), 139-146.
Background Reference 03
St-Jacques, S., Cymerman, U. R. S. Z. U. L. A., Pece, N. A. D. I. A., Letarte, M. (1994) . Molecular characterization and in situ localization of murine endoglin reveal that it is a transforming growth factor-beta binding protein of endothelial and stromal cells.Endocrinology,134 (6), 2645-2657.
Other Product Names
AIM, VEA, AI452015, 5830438K24Rik, Cd69
Tested Applications
Flow
Physical Properties
Liquid
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