CD69 Antibody [FN50] (PE)
Product Specifications
Background
The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) . It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.
NCBI Gene ID
969
Swiss Prot
Q07108
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
FN50
Conjugation
PE
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-815
Fragment
Mouse IgG1, kappa
Specificity
The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) .
Symbol
CD69
NCBI Official Name
CD69 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., Corradin, S. B. (1997) . Expression and function of the early activation antigen CD69 in murine macrophages.Journal of leukocyte biology,62 (3), 349-355.
Background Reference 02
Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., Shevach, E. M. (1988) . Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.The Journal of Immunology,141 (2), 369-376.
Background Reference 03
Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., Cohen, P. L. (1993) . Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.The Journal of Immunology,150 (2), 673-682.
Other Product Names
AIM, EA1, MLR-3, CLEC2C, GP32/28, BL-AC/P26, CD69
Tested Applications
Flow
Physical Properties
Liquid
Curated Selection
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