CD69 Antibody [FN50] (FITC)

Product Specifications

Background

The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) . It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.

NCBI Gene ID

969

Swiss Prot

Q07108

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

FN50

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

Symbol

CD69

NCBI Official Name

CD69 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Lu, H., Crawford, R. B., North, C. M., Kaplan, B. L., Kaminski, N. E. (2009) . Establishment of an immunoglobulin m antibody-forming cell response model for characterizing immunotoxicity in primary human B cells.Toxicological sciences,112 (2), 363-373.

Background Reference 02

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 03

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.