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CD59 Antibody [OV9A2] (PE)

Product Specifications

Background

The OV9A2 monoclonal antibody specifically reacts with human CD59 (Protectin), a 19-25 kDA GPI-anchored glycoprotein. CD59 is expressed on hematopoietic and non-hematopoietic cells including lymphocytes, granulocytes, erythrocytes, monocytes and neurons. CD59 can inhibit complement cytolytic activity and the assembly of the membrane attack complex when bound to C8 and C9 complement components. It is involved in T cell activation and modulates T cell adhesion through interaction with CD2.

NCBI Gene ID

966

Swiss Prot

P13987

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

OV9A2

Conjugation

PE

Type

Primary Antibodies

Field of Research

Innate Immunity, Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-811

Fragment

Mouse IgG1, kappa

Specificity

The OV9A2 monoclonal antibody specifically reacts with human CD59 (Protectin), a 19-25 kDA GPI-anchored glycoprotein.

Symbol

CD59

NCBI Official Name

CD59 molecule, complement regulatory protein

NCBI Organism

Homo sapiens

Background Reference 01

Lu, H., Crawford, R. B., North, C. M., Kaplan, B. L., Kaminski, N. E. (2009) . Establishment of an immunoglobulin m antibody-forming cell response model for characterizing immunotoxicity in primary human B cells.Toxicological sciences,112 (2), 363-373.

Background Reference 02

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 03

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Other Product Names

1F5, EJ16, EJ30, EL32, G344, MIN1, MIN2, MIN3, MIRL, HRF20, MACIF, MEM43, MIC11, MSK21, 16.3A5, HRF-20, MAC-IP, p18-20, CD59

Tested Applications

Flow

Physical Properties

Liquid

Curated Selection

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