CD29 Antibody [HMb1-1] (PE)

Product Specifications

Background

The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.

NCBI Gene ID

16412;24511

Swiss Prot

P09055

Host

Hamster

Reactivity

Mouse, Rat

Clonality

Monoclonal

Clone

HMb1-1

Conjugation

Type

Primary Antibodies

Field of Research

Cancer

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-798

Fragment

Armenian Hamster IgG

Specificity

The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain.

Symbol

Itgb1

NCBI Official Name

Integrin beta 1 (fibronectin receptor beta)

NCBI Organism

Mus musculus; Rattus norvegicus

Background Reference 01

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 02

Kleinewietfeld, M., Starke, M., Di Mitri, D., Borsellino, G., Battistini, L., Rtzschke, O., Falk, K. (2009) . CD49d provides access to untouched human Foxp3+ Treg free of contaminating effector cells.Blood,113 (4), 827-836.

Background Reference 03

Hemler, M. E. (1990) . VLA proteins in the integrin family: structures, functions, and their role on leukocytes.Annual review of immunology,8 (1), 365-400.

Other Product Names

CD29, Fnrb, gpIIa, Gm9863, AA409975, AA960159, 4633401G24Rik, ENSMUSG00000051907, Itgb1

Tested Applications

Flow

Physical Properties

Liquid

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