What is the catalog number for CD29 Antibody [HMb1-1] (PE)?

The catalog number for CD29 Antibody [HMb1-1] (PE) is 76-796.

What sizes are available for CD29 Antibody [HMb1-1] (PE)?

CD29 Antibody [HMb1-1] (PE) is available in the following size(s): 0.1 mg.

Is CD29 Antibody [HMb1-1] (PE) in stock?

CD29 Antibody [HMb1-1] (PE) is currently made to order / not held in immediate stock. Contact us for lead time.

CD29 Antibody [HMb1-1] (PE)

Product Specifications

Background

The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.

NCBI Gene ID

16412;24511

Swiss Prot

P09055

Host

Hamster

Reactivity

Mouse, Rat

Clonality

Monoclonal

Clone

HMb1-1

Conjugation

Type

Primary Antibodies

Field of Research

Cancer

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Armenian Hamster IgG

Specificity

The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDA molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain.

Symbol

Itgb1

NCBI Official Name

Integrin beta 1 (fibronectin receptor beta)

NCBI Organism

Mus musculus; Rattus norvegicus

Background Reference 01

Ridger, V. C., Wagner, B. E., Wallace, W. A., Hellewell, P. G. (2001) . Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation.The Journal of Immunology,166 (5), 3484-3490.

Background Reference 02

Noto, K., Kato, K., Okumura, K., Yagita, H. (1995) . Identification and functional characterization of mouse CD29 with a mAb.International immunology,7 (5), 835-842.

Background Reference 03

Sangaletti, S., Di Carlo, E., Gariboldi, S., Miotti, S., Cappetti, B., Parenza, M., ... Colombo, M. P. (2008) . Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis.Cancer research,68 (21), 9050-9059.