CD29 Antibody [TS2/16] (FITC)
Product Specifications
Background
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells. It forms the VLA- (1-6) molecules with integrin alpha- (1-6) and is involved in the adhesion between cell-cell and cell-matrix. The TS2/16 antibody has been found to activate beta 1 integrins.
NCBI Gene ID
3688
Swiss Prot
P05556
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
TS2/16
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Cancer
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The TS2/16 moncolonal antibody specifically reacts with human CD29 (Integrin beta1), a 130 kDA type I glycoprotein expressed on hematopoietic and non-hematopoietic cells.
Symbol
ITGB1
NCBI Official Name
Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
NCBI Organism
Homo sapiens
Background Reference 01
Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., ... Strominger, J. L. (1984) . Glycoproteins of 210,000 and 130,000 mw on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.The Journal of Immunology,132 (6), 3011-3018.
Background Reference 02
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 03
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., Springer, T. A. (1982) . Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.Proceedings of the National Academy of Sciences,79 (23), 7489-7493.
Other Product Names
CD29, FNRB, MDF2, VLAB, GPIIA, MSK12, VLA-BETA, ITGB1
Tested Applications
Flow
Physical Properties
Liquid
Frequently Asked Questions
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