CD19 Antibody [HIB19] (FITC)
Product Specifications
Background
The HIB19 monoclonal antibody specifically reacts with human CD19, a 95kDA type 1 transmembrane glycoprotein also known as B4. It is expressed on all stages of B cell development except for final plasma cells and on follicular dendritic cells. CD19 plays a role in B cell proliferation, activation, and differentiation. It functions as a BCR co-receptor with CD21 and CD81.
NCBI Gene ID
930
Swiss Prot
P15391
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
HIB19
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The HIB19 monoclonal antibody specifically reacts with human CD19, a 95kDA type 1 transmembrane glycoprotein also known as B4.
Symbol
CD19
NCBI Official Name
CD19 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Hemler, M. E., Sanchez-Madrid, F., Flotte, T. J., Krensky, A. M., Burakoff, S. J., Bhan, A. K., ... Strominger, J. L. (1984) . Glycoproteins of 210,000 and 130,000 mw on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines.The Journal of Immunology,132 (6), 3011-3018.
Background Reference 02
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 03
Sanchez-Madrid, F., Krensky, A. M., Ware, C. F., Robbins, E., Strominger, J. L., Burakoff, S. J., Springer, T. A. (1982) . Three distinct antigens associated with human T-lymphocyte-mediated cytolysis: LFA-1, LFA-2, and LFA-3.Proceedings of the National Academy of Sciences,79 (23), 7489-7493.
Other Product Names
B4, CVID3, CD19
Tested Applications
Flow
Physical Properties
Liquid
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