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CD19 Antibody [1D3] (APC)

Product Specifications

Background

The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells. CD19 associates with CD21, CD81 and MHC class II to form a multi-molecular complex that initiates the mature B lymphocyte activation by interaction with the B-cell receptors. CD 19 enhances the B cell proliferation, development and activation, and the maturation of memory B cells. In CD19-deficient mice, the generation and maturation of B lymphocytes in the bone marrow and periphery are affected.

NCBI Gene ID

12478

Swiss Prot

P25918

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

1D3

Conjugation

APC

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-787

Fragment

Rat IgG2a, kappa

Specificity

The 1D3 monoclonal antibody specifically reacts with mouse CD19, a 95 kDa transmembrane glycoprotein, a member of the Ig superfamily and a B cell-lineage differentiation antigen expressed by all the B lymphocyte development stages, except for the terminally differentiated plasma cells.

Symbol

Cd19

NCBI Official Name

CD19 antigen

NCBI Organism

Mus musculus

Background Reference 01

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 02

Schlossman, S., L. Bloumsell, et al. eds (1995) . Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York

Background Reference 03

McMichael, A. J., Beverley, P. C. L., Cobbold, S., Crumpton, M. J., Gilks, W., Gotch, F. M., ... Waldman, H. (1987) . Leukocyte typing III.White Cell Differentiation Antigens, 733-786.

Other Product Names

AW495831, Cd19

Tested Applications

Flow

Physical Properties

Liquid

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