CD48 Antibody [156-4H9]
Product Specifications
Background
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.
NCBI Gene ID
962
Swiss Prot
P09326
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
156-4H9
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity, Immunology, Stem Cell
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-757
Fragment
Mouse IgG1
Specificity
The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily.
Symbol
CD48
NCBI Official Name
CD48 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... Yagita, H. (1992) . CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.The Journal of experimental medicine,176 (5), 1241-1249.
Background Reference 02
Qin, L., Chavin, K. D., Lin, J., Yagita, H., Bromberg, J. S. (1994) . Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival.The Journal of experimental medicine,179 (1), 341-346.
Background Reference 03
Chavin, K. D., Qin, L., Lin, J., Woodward, J., Baliga, P., Kato, K., ... Bromberg, J. S. (1994) . Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo.International immunology,6 (5), 701-709.
Other Product Names
BCM1, BLAST, hCD48, mCD48, BLAST1, SLAMF2, MEM-102, CD48
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
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