CD48 Antibody [156-4H9]

Product Specifications

Background

The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily. CD48 was previously known as BCM1 in mice, Blast-1 in humans, and OX-45 in rats. Its ligands are CD2 and CD244 and it is expressed on leukocytes to the exclusion of non-hematopoietic cells and its expression increases in B cells upon activation.

NCBI Gene ID

962

Swiss Prot

P09326

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

156-4H9

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity, Immunology, Stem Cell

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Mouse IgG1

Specificity

The 156-4H9 monoclonal antibody specifically reacts with human CD48, a GPI-linked glycoprotein in the Ig superfamily.

Symbol

CD48

NCBI Official Name

CD48 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Kato, K., Koyanagi, M., Okada, H., Takanashi, T., Wong, Y. W., Williams, A. F., ... Yagita, H. (1992) . CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.The Journal of experimental medicine,176 (5), 1241-1249.

Background Reference 02

Qin, L., Chavin, K. D., Lin, J., Yagita, H., Bromberg, J. S. (1994) . Anti-CD2 receptor and anti-CD2 ligand (CD48) antibodies synergize to prolong allograft survival.The Journal of experimental medicine,179 (1), 341-346.

Background Reference 03

Chavin, K. D., Qin, L., Lin, J., Woodward, J., Baliga, P., Kato, K., ... Bromberg, J. S. (1994) . Anti-CD48 (murine CD2 ligand) mAbs suppress cell mediated immunity in vivo.International immunology,6 (5), 701-709.