CD38 Antibody [90]
Product Specifications
Background
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, and macrophages. In the mouse as opposed to the human, CD38 expression is downregulated on mouse germinal center B cells and plasma cells. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
NCBI Gene ID
12494
Swiss Prot
P56528
Host
Mouse
Reactivity
Mouse
Clonality
Monoclonal
Clone
90
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Other
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-754
Fragment
Mouse IgG2a, kappa
Specificity
The 90 monoclonal antibody specifically bind to mouse CD38, a type II transmembrane glycoprotein.
Symbol
Cd38
NCBI Official Name
CD38 antigen
NCBI Organism
Mus musculus
Background Reference 01
Gonzlez-lvaro, I., Domnguez-Jimnez, C., Ortiz, A. M., Nez-Gonzlez, V., Roda-Navarro, P., Fernndez-Ruiz, E., ... Snchez-Madrid, F. (2006) . Interleukin-15 and interferon- gammaparticipate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production.Arthritis research therapy,8 (4), R88.
Background Reference 02
Katagiri, T., Qi, Z., Ohtake, S., Nakao, S. (2011) . GPI‐anchored protein‐deficient T cells in patients with aplastic anemia and low‐risk myelodysplastic syndrome: implications for the immunopathophysiology of bone marrow failure.European journal of haematology,86 (3), 226-236.
Background Reference 03
Yokoyama, S., Staunton, D., Fisher, R., Amiot, M., Fortin, J. J., Thorley-Lawson, D. A. (1991) . Expression of the Blast-1 activation/adhesion molecule and its identification as CD48.The Journal of immunology,146 (7), 2192-2200.
Other Product Names
ADPRC 1, Cd38-rs1, Cd38
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
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