CD38 Antibody [HIT2] (APC)
Product Specifications
Background
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.
NCBI Gene ID
952
Swiss Prot
P28907
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
HIT2
Conjugation
APC
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-752
Fragment
Mouse IgG1, kappa
Specificity
The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein.
Symbol
CD38
NCBI Official Name
CD38 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Oliver, A. M., Martin, F., Kearney, J. F. (1997) . Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.The Journal of Immunology,158 (3), 1108-1115.
Background Reference 02
Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., Zlotnik, A. (1995) . CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha -beta TCR+ CD4 CD8 thymocytes.International immunology,7 (2), 213-221.
Background Reference 03
Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., Howard, M. (1995) . Murine CD38: an immunoregulatory ectoenzyme.Immunology today,16 (10), 469-473.
Other Product Names
T10, ADPRC 1, CD38
Tested Applications
Flow
Physical Properties
Liquid
Curated Selection
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