CD38 Antibody [HIT2] (APC)

Product Specifications

Background

The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein. CD38 is expressed on activated T cells, plasma cells, monocytes, macrophages, dendritic cells, and thymocytes. CD38 displays cyclase and hydrolase enzymatic activity and is involved in lymphocyte adhesion, activation, and cell signaling. Its ligand is CD31.

NCBI Gene ID

952

Swiss Prot

P28907

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

Conjugation

APC

Type

Primary Antibodies

Field of Research

Stem Cell

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HIT2 monoclonal antibody specifically bind to human CD38, a 45kda type II transmembrane glycoprotein.

Symbol

CD38

NCBI Official Name

CD38 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Oliver, A. M., Martin, F., Kearney, J. F. (1997) . Mouse CD38 is down-regulated on germinal center B cells and mature plasma cells.The Journal of Immunology,158 (3), 1108-1115.

Background Reference 02

Bean, A. G., Godfrey, D. I., Ferlin, W. G., Santos-Argumedo, L., Parkhouse, R. M. E., Howard, M. C., Zlotnik, A. (1995) . CD38 expression on mouse T cells: CD38 defines functionally distinct subsets of alpha -beta TCR+ CD4 CD8 thymocytes.International immunology,7 (2), 213-221.

Background Reference 03

Lund, F., Solvason, N., Grimaldi, J. C., Michael, R., Parkhouse, E., Howard, M. (1995) . Murine CD38: an immunoregulatory ectoenzyme.Immunology today,16 (10), 469-473.