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CD8b Antibody [H35-17.2] (PE)

Product Specifications

Background

The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3. CD8 is a T cell surface antigen co-receptor that interacts with MHC class I molecules on antigen presenting cells. It is expressed as a heterodimer with the alpha cd8 chain. The H35-17.2 antibody blocks T cell-mediated cytolysis of allogeneic lymphoma cells.

NCBI Gene ID

12526

Swiss Prot

P10300

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

H35-17.2

Conjugation

PE

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-719

Fragment

Rat IgG2b, kappa

Specificity

The H35-17.2 monoclonal antibody specifically reacts the mouse cd8 beta, a 32 kDa chain also known as Ly-3 and Lyt-3.

Symbol

Cd8b1

NCBI Official Name

CD8 antigen, beta chain 1

NCBI Organism

Mus musculus

Background Reference 01

Lefrancois, L. (1991) . Phenotypic complexity of intraepithelial lymphocytes of the small intestine.The Journal of Immunology,147 (6), 1746-1751.

Background Reference 02

Walker, I. D., Murray, B. J., Hogarth, P. M., Kelso, A., McKenzie, I. F. (1984) . Comparison of thymic and peripheral T cell Ly‐2/3 antigens.European journal of immunology,14 (10), 906-910.

Background Reference 03

THOMA-USZYNSKI, S., LADEL, C., KAUFMANN, S. (1997) . Abscess formation in Listeria monocytogenes-infected gamma-delta T cell deficient mouse mutants involves alpha -beta T cells.Microbial pathogenesis,22 (2), 123-128.

Other Product Names

Cd8b, Ly-3, Ly-C, Lyt-3, Cd8b1

Tested Applications

Flow

Physical Properties

Liquid

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