Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

CD8a Antibody [2.43]

Product Specifications

Background

The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen. CD8a (the alpha chains) form heterodimers with CD8b (the beta chains) or homodimers (alpha-alpha), which occur as receptors on the surface of the majority of thymocytes. A subpopulation of mature T lymphocytes expresses the CD8 alpha beta (alpha beta TCR T cells), and a subpopulation of intestinal intraepithelial lymphocytes and dendritic cells express CD8a without CD8b. CD8 interacts with the mouse major histocompatibility complex class I (MHC class I) molecules on antigen-presenting cells or epithelial cells.

NCBI Gene ID

12525

Swiss Prot

P01731

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

2.43

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-646

Fragment

Rat IgG2b

Specificity

The 2.43 monoclonal antibody specifically reacts with mouse CD8 antigen.

Symbol

Cd8a

NCBI Official Name

CD8 antigen, alpha chain

NCBI Organism

Mus musculus

Background Reference 01

Salem, M. L., Hossain, M. S. (2000) . In vivo acute depletion of CD8+ T cells before murine cytomegalovirus infection upregulated innate antiviral activity of natural killer cells. International journal of immunopharmacology,22 (9), 707-718.

Background Reference 02

Kruisbeek, A. M. (1991) . In Vivo Depletion of CD4 and CD8 Specific T Cells.Current protocols in immunology, 4-1.

Background Reference 03

Davies, A., Kalb, S., Liang, B., Aldrich, C. J., Lemonnier, F. A., Jiang, H., ... Soloski, M. J. (2003) . A peptide from heat shock protein 60 is the dominant peptide bound to Qa-1 in the absence of the MHC class Ia leader sequence peptide Qdm.The Journal of Immunology,170 (10), 5027-5033.

Other Product Names

Ly-2, Ly-B, Ly-35, Lyt-2, BB154331, Cd8a

Tested Applications

Flow, Functional Assays, IHC

Physical Properties

Liquid

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

LZTFL1 (C-6) Alexa Fluor® 546
sc-376022 AF546 200 µg/mL

LZTFL1 (C-6) Alexa Fluor® 546

Ask
View Details
Human CD40L multimeric Recombinant Protein DDDDK Tag Lyophilized
MBS8431570-01 0.01 mg

Human CD40L multimeric Recombinant Protein DDDDK Tag Lyophilized

Ask
View Details
Human CD40L multimeric Recombinant Protein DDDDK Tag Lyophilized
MBS8431570-02 5x 0.01 mg

Human CD40L multimeric Recombinant Protein DDDDK Tag Lyophilized

Ask
View Details
Mouse Ccn2 (NM_010217) AAV Particle
MR226802A1V 250 µL

Mouse Ccn2 (NM_010217) AAV Particle

Ask
View Details
Ppp2r3a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
37476116 3 x 1.0 µg

Ppp2r3a sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)

Ask
View Details
HIRIP3 Antibody (Center)
MBS9203331-01 0.08 mL

HIRIP3 Antibody (Center)

Ask
View Details