CD57 Antibody [TBO1]
Product Specifications
Background
The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle. It is reported that the molecule is involved in cell-matrix interactions and is upregulated in some disease states.
NCBI Gene ID
27087
Swiss Prot
Q9P2W7
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
TBO1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-634
Fragment
Mouse IgM
Specificity
The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle.
Symbol
B3GAT1
NCBI Official Name
Beta-1,3-glucuronyltransferase 1
NCBI Organism
Homo sapiens
Background Reference 01
Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005) . Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175 (12), 8415-8423.
Background Reference 02
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 03
Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985) . Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66 (1), 64-68.
Other Product Names
NK1, CD57, HNK1, LEU7, NK-1, GLCATP, GLCUATP, B3GAT1
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
Curated Selection
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