CD57 Antibody [TBO1]

Product Specifications

Background

The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle. It is reported that the molecule is involved in cell-matrix interactions and is upregulated in some disease states.

NCBI Gene ID

27087

Swiss Prot

Q9P2W7

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

TBO1

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Mouse IgM

Specificity

The TBO1 monoclonal antibody specifically binds to human CD57, a 110 kDA glycoprotein expressed on a subset of natural killer lymphocytes, cells, neural cells and striated muscle.

Symbol

B3GAT1

NCBI Official Name

Beta-1,3-glucuronyltransferase 1

NCBI Organism

Homo sapiens

Background Reference 01

Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005) . Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175 (12), 8415-8423.

Background Reference 02

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 03

Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985) . Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66 (1), 64-68.