CD27 Antibody [LG.7F9]
Product Specifications
Background
The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.7F9 antibody is cross-reactive human, mouse, and rat CD27.
NCBI Gene ID
939
Swiss Prot
P26842
Host
Hamster
Reactivity
Human
Clonality
Monoclonal
Clone
LG.7F9
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Immunology, Apoptosis
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Fragment
Armenian Hamster IgG
Specificity
The LG.7F9 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. .
Symbol
CD27
NCBI Official Name
CD27 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005) . Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175 (12), 8415-8423.
Background Reference 02
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 03
Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985) . Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66 (1), 64-68.
Other Product Names
T14, S152, Tp55, TNFRSF7, S152. LPFS2, CD27
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
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