CD27 Antibody [LG.3A10]

Product Specifications

Background

The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily. It is expressed on memory B cells, NK cells, mature T cells, and a subset of thymocytes. Cd27 is involved in the interactions between B and T cells through its ligand CD70. The LG.3A10 antibody is cross-reactive with human, mouse and rat CD27.

NCBI Gene ID

21940

Swiss Prot

P41272

Host

Hamster

Reactivity

Human, Mouse

Clonality

Monoclonal

Clone

LG.3A10

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology, Apoptosis

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Armenian Hamster IgG

Specificity

The LG.3A10 monoclonal antibody binds to CD27, 45kDA molecule in the Tumor Necrosis Factor Receptor (TNFR) superfamily.

Symbol

Cd27

NCBI Official Name

CD27 antigen

NCBI Organism

Mus musculus

Background Reference 01

Palmer, B. E., Blyveis, N., Fontenot, A. P., Wilson, C. C. (2005) . Functional and phenotypic characterization of CD57+ CD4+ T cells and their association with HIV-1-induced T cell dysfunction.The Journal of Immunology,175 (12), 8415-8423.

Background Reference 02

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 03

Prince, H. E., Kreiss, J. K., Kasper, C. K., Kleinman, S., Saunders, A. M., Waldbeser, L., ... Kaplan, H. S. (1985) . Distinctive lymphocyte subpopulation abnormalities in patients with congenital coagulation disorders who exhibit lymph node enlargement.Blood,66 (1), 64-68.