CD27 Antibody [O323] (FITC)
Product Specifications
Background
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells. CD27 is upregulated by T lymphocytes stimulation, and binds to CD70, enhancing the interaction between T and B lymphocytes. CD27 is a marker of memory B cells.
NCBI Gene ID
939
Swiss Prot
P26842
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
O323
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Immunology, Apoptosis
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgG1, kappa
Specificity
The O323 monoclonal antibody specifically binds to the human CD27, which is a lymphocyte-specific member of the TNF/NGF-R family, expressed on a subset of human thymocytes and the majority of the mature T cells.
Symbol
CD27
NCBI Official Name
CD27 molecule
NCBI Organism
Homo sapiens
Background Reference 01
Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 02
Correia, D. V., Fogli, M., Hudspeth, K., da Silva, M. G., Mavilio, D., Silva-Santos, B. (2011) . Differentiation of human peripheral blood Vdelta-1+ T cells expressing the natural cytotoxicity receptor NKp30 for recognition of lymphoid leukemia cells.Blood,118 (4), 992-1001.
Other Product Names
T14, S152, Tp55, TNFRSF7, S152. LPFS2, CD27
Tested Applications
Flow
Physical Properties
Liquid
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