CD5 Antibody [UCHT2] (PerCP-Cy5.5)

Product Specifications

Background

The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.

NCBI Gene ID

921

Swiss Prot

P06127

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

UCHT2

Conjugation

PerCP-Cy5.5

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein.

Symbol

CD5

NCBI Official Name

CD5 molecule

NCBI Organism

Homo sapiens

Background Reference 01

McMichael, A. J. (1987) .Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA.

Background Reference 02

Lankester, A. C., van Schijndel, G. M., Cordell, J. L., van Noesel, C. J., van Lier, R. A. (1994) . CD5 is associated with the human B cell antigen receptor complex.European journal of immunology,24 (4), 812-816.

Background Reference 03

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009) . A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57 (12), 1159-1167.