CD5 Antibody [UCHT2] (PE)

Product Specifications

Background

The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein. CD5 is expressed on mature T cells, a subset of B cells, and peripheral blood dendritic cells. B cells that are CD5+ produce mostly IgM polyreactive antibodies. Its ligand is CD72, which is involved in T, B cell proliferation and interaction. The UCT2 antibody also recognizes non-human primate CD5.

NCBI Gene ID

921

Swiss Prot

P06127

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

UCHT2

Conjugation

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The UCHT2 monoclonal antibody specifically reacts with human CD5, a 67 kda type 1 transmembrane glycoprotein.

Symbol

CD5

NCBI Official Name

CD5 molecule

NCBI Organism

Homo sapiens

Background Reference 01

McMichael, A. J. (1987) .Leucocyte typing III: white cell differentiation antigens. Oxford University Press, USA.

Background Reference 02

Lankester, A. C., van Schijndel, G. M., Cordell, J. L., van Noesel, C. J., van Lier, R. A. (1994) . CD5 is associated with the human B cell antigen receptor complex.European journal of immunology,24 (4), 812-816.

Background Reference 03

Kap, Y. S., van Meurs, M., van Driel, N., Koopman, G., Melief, M. J., Brok, H. P., ... A't Hart, B. (2009) . A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates.Journal of Histochemistry Cytochemistry,57 (12), 1159-1167.