CD86 Antibody [24F] (FITC)

Product Specifications

Background

The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions. The 24F antibody is capable of blocking the co-stimulatory activity of CD86.

NCBI Gene ID

56822

Host

Mouse

Reactivity

Rat

Clonality

Monoclonal

Clone

24F

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.

Symbol

Cd86

NCBI Official Name

CD86 molecule

NCBI Organism

Rattus norvegicus

Background Reference 01

Maeda, K., Sato, T., Azuma, M., Yagita, H., Okumura, K. (1997) . Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology,9 (7), 993-1000.