CD66b Antibody [G10F5]
Product Specifications
Background
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family. CD66b is expressed on granulocytes, neutrophils, and eosinophils. It is reported that this molecule plays a role in regulating neutrophil activation and cellular adhesion. It was previously classified as CD67, but renamed CD66b in the Fifth HLDA Workshop.
NCBI Gene ID
1088
Swiss Prot
P31997
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
G10F5
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-590
Fragment
Mouse IgM, kappa
Specificity
The G10F5 monoclonal antibody specifically reacts with human CD66b, a 100kDa glycosylphosphatidylinositol (GPI) linked protein in the granulocyte-specific activation family.
Symbol
CEACAM8
NCBI Official Name
Carcinoembryonic antigen-related cell adhesion molecule 8
NCBI Organism
Homo sapiens
Background Reference 01
Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.
Background Reference 02
Lund-Johansen, F. R. I. D. T. J. O. F., Olweus, J. O. H. A. N. N. A., Horejsi, V. A. C. L. A. V., Skubitz, K. M., Thompson, J. S., Vilella, R., Symington, F. W. (1992) . Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65) .The Journal of Immunology,148 (10), 3221-3229.
Background Reference 03
Schmidt, T., Zndorf, J., Grger, T., Brandenburg, K., Reiners, A. L., Zinserling, J., Schnitzler, N. (2012) . CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus.Journal of leukocyte biology,91 (5), 791-802.
Other Product Names
CD67, CGM6, CD66b, NCA-95, CEACAM8
Tested Applications
Flow, IHC
Physical Properties
Liquid
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