CD15 Antibody [HI98] (APC)

Product Specifications

Background

The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL) . CD15 is expressed on most granulocytes and monocytes to the exclusion of lymphocytes and basophils. It is involved in cell adhesion, chemotaxis, and phagocytosis.

NCBI Gene ID

2526

Swiss Prot

P22083

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HI98

Conjugation

APC

Type

Primary Antibodies

Field of Research

Innate Immunity, Stem Cell

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgM, kappa

Specificity

The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL) .

Symbol

FUT4

NCBI Official Name

Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)

NCBI Organism

Homo sapiens

Background Reference 01

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 02

Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997) .The leucocyte antigen factsbook. Academic Press.

Background Reference 03

Lund-Johansen, F., Olweus, J., Horejsi, V., Skubitz, K. M., Thompson, J. S., Vilella, R., Symington, F. W. (1992) . Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65) .Journal of immunology (Baltimore, Md.: 1950),148 (10), 3221.