CD15 Antibody [HI98] (FITC)
Product Specifications
Background
The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL) . CD15 is expressed on most granulocytes and monocytes to the exclusion of lymphocytes and basophils. It is involved in cell adhesion, chemotaxis, and phagocytosis.
NCBI Gene ID
2526
Swiss Prot
P22083
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Clone
HI98
Conjugation
FITC
Type
Primary Antibodies
Field of Research
Innate Immunity, Stem Cell
Purification
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.
Fragment
Mouse IgM, kappa
Specificity
The HI98 monoclonal antibody specifically reacts with CD15, a 220 kDa carbohydrate moiety also known as SSEA-1, Lewis 3-fucosyl-N-acetyllactosamine (3-FAL) .
Symbol
FUT4
NCBI Official Name
Fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
NCBI Organism
Homo sapiens
Background Reference 01
Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.
Background Reference 02
Barclay, A. N., Brown, M. H., Law, S. A. K. A., McKnight, A. J., Tomlinson, M. G., van der Merwe, P. A. (1997) .The leucocyte antigen factsbook. Academic Press.
Background Reference 03
Lund-Johansen, F., Olweus, J., Horejsi, V., Skubitz, K. M., Thompson, J. S., Vilella, R., Symington, F. W. (1992) . Activation of human phagocytes through carbohydrate antigens (CD15, sialyl-CD15, CDw17, and CDw65) .Journal of immunology (Baltimore, Md.: 1950),148 (10), 3221.
Other Product Names
LeX, CD15, ELFT, FCT3A, FUTIV, SSEA-1, FUC-TIV, FUT4
Tested Applications
Flow
Physical Properties
Liquid
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