What is the catalog number for CD45 Antibody [HI30] (APC-Cy7)?

The catalog number for CD45 Antibody [HI30] (APC-Cy7) is 76-453.

What sizes are available for CD45 Antibody [HI30] (APC-Cy7)?

CD45 Antibody [HI30] (APC-Cy7) is available in the following size(s): 100 Tests.

Is CD45 Antibody [HI30] (APC-Cy7) in stock?

CD45 Antibody [HI30] (APC-Cy7) is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

CD45 Antibody [HI30] (APC-Cy7)

Product Specifications

Background

The HI30 monoclonal antibody specifically reacts with the 180 kDa, 190 kDa, 205 kDa, and 220 kDa isoforms of the human leukocyte common antigen (LCA) CD45. It is expressed on lymphocytes, granulocytes, monocytes, thymocytes, and eosinophils, but not on mature erythrocytes, platelets, mature erythroid cells of bone marrow, and non-hematopoietic tissues. CD45 is essential for T cell activation and the tyrosine phosphatase activity of its intracellular region is integral for signal transduction.

NCBI Gene ID

5788

Swiss Prot

P08575

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HI30

Conjugation

APC-Cy7

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HI30 monoclonal antibody specifically reacts with the 180 kDa, 190 kDa, 205 kDa, and 220 kDa isoforms of the human leukocyte common antigen (LCA) CD45.

Symbol

PTPRC

NCBI Official Name

Protein tyrosine phosphatase, receptor type, C

NCBI Organism

Homo sapiens

Background Reference 01

Knapp W (1989) Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 02

Ninomiya, M., Abe, A., Katsumi, A., Xu, J., Ito, M., Arai, F., ... Naoe, T. (2006) . Homing, proliferation and survival sites of human leukemia cells in vivo in immunodeficient mice.Leukemia,21 (1), 136-142.

Background Reference 03

Yoshino, N., AMI, Y., TERAO, K., TASHIRO, F., HONDA, M. (2000) . Upgrading of flow cytometric analysis for absolute counts, cytokines and other antigenic molecules of cynomolgus monkeys (Macaca fascicularis) by using anti-human cross-reactive antibodies.Experimental Animals,49 (2), 97-110.