CD24 Antibody [M1/69]

Product Specifications

Background

The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein. CD24 is known as the Heat Stable Antigen (HAS or HsAG) and is found on epithelial cells, thymocytes, monocytes, erythrocytes, granulocytes, dendritic cells and lymphocytes to the exclusion of NK cells. It is useful in delineating the stages of lymphocyte development and is involved in the costimulation of CD4+ T cells by B cells. CD62P (P-Selectin) is the reported ligand of CD24.

NCBI Gene ID

12484

Swiss Prot

P24807

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

M1/69

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Rat IgG2b, kappa

Specificity

The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein.

Symbol

Cd24a

NCBI Official Name

CD24a antigen

NCBI Organism

Mus musculus

Background Reference 01

Alterman, L. A., Crispe, I. N., Kinnon, C. (1990) . Characterization of the murine heat‐stable antigen: An hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies.European journal of immunology,20 (7), 1597-1602.

Background Reference 02

Crowley, M., Inaba, K., Witmer-Pack, M., Steinman, R. M. (1989) . The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus.Cellular immunology,118 (1), 108-125.

Background Reference 03

Wenger, R. H., Rochelle, J. M., Seldin, M. F., Khler, G., Nielsen, P. J. (1993) . The heat stable antigen (mouse CD24) gene is differentially regulated but has a housekeeping promoter.Journal of Biological Chemistry,268 (31), 23345-23352.