CD24 Antibody [M1/69]
Product Specifications
Background
The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein. CD24 is known as the Heat Stable Antigen (HAS or HsAG) and is found on epithelial cells, thymocytes, monocytes, erythrocytes, granulocytes, dendritic cells and lymphocytes to the exclusion of NK cells. It is useful in delineating the stages of lymphocyte development and is involved in the costimulation of CD4+ T cells by B cells. CD62P (P-Selectin) is the reported ligand of CD24.
NCBI Gene ID
12484
Swiss Prot
P24807
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
M1/69
Conjugation
Unconjugated
Type
Primary Antibodies, Functional Antibodies
Field of Research
Immunology
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-402
Fragment
Rat IgG2b, kappa
Specificity
The M1/69 monoclonal antibody specifically reacts with mouse CD24, variably glycosylated GPI-anchored membrane protein.
Symbol
Cd24a
NCBI Official Name
CD24a antigen
NCBI Organism
Mus musculus
Background Reference 01
Alterman, L. A., Crispe, I. N., Kinnon, C. (1990) . Characterization of the murine heat‐stable antigen: An hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies.European journal of immunology,20 (7), 1597-1602.
Background Reference 02
Crowley, M., Inaba, K., Witmer-Pack, M., Steinman, R. M. (1989) . The cell surface of mouse dendritic cells: FACS analyses of dendritic cells from different tissues including thymus.Cellular immunology,118 (1), 108-125.
Background Reference 03
Wenger, R. H., Rochelle, J. M., Seldin, M. F., Khler, G., Nielsen, P. J. (1993) . The heat stable antigen (mouse CD24) gene is differentially regulated but has a housekeeping promoter.Journal of Biological Chemistry,268 (31), 23345-23352.
Other Product Names
HSA, Cd24, Ly-52, nectadrin, Cd24a
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
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