What is the catalog number for CD14 Antibody [61D3] (FITC)?

The catalog number for CD14 Antibody [61D3] (FITC) is 76-390.

What sizes are available for CD14 Antibody [61D3] (FITC)?

CD14 Antibody [61D3] (FITC) is available in the following size(s): 25 Tests.

Is CD14 Antibody [61D3] (FITC) in stock?

CD14 Antibody [61D3] (FITC) is currently made to order / not held in immediate stock. Contact us for lead time.

CD14 Antibody [61D3] (FITC)

Product Specifications

Background

The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-kappaB.

NCBI Gene ID

929

Swiss Prot

P08571

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

61D3

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The 61D3 monoclonal antibody specifically reacts with CD14, a cell surface anchored glycoprotein that is primarily expressed on monocytes, inerfollicular macrophages, and a subset of dendritic cells.

Symbol

CD14

NCBI Official Name

CD14 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 02

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Background Reference 03

Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., Gregory, C. D. (1998) . Human CD14 mediates recognition and phagocytosis of apoptotic cells.Nature,392 (6675), 505-509.