CD14 Antibody [61D3]

Product Specifications

Background

The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS) . It is expressed on some dendritic cells, monocytes, and neutrophils. CD14 is involved in the body’s innate immune response and cytokine expression in monocytes and neutrophils.

NCBI Gene ID

929

Swiss Prot

P08571

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

61D3

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The 61D3 monclonal antibody specifically binds to human CD14, a co-receptor for bacterial lipopolysaccharides (LPS) .

Symbol

CD14

NCBI Official Name

CD14 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 02

Leucocyte Typing VI: White Cell Differentiation Antigens: Proceedings of the Sixth International Workshop and Conference Held in Kobe, Japan, 10-14 November 1996. Garland Pub., 1998.

Background Reference 03

Devitt, A., Moffatt, O. D., Raykundalia, C., Capra, J. D., Simmons, D. L., Gregory, C. D. (1998) . Human CD14 mediates recognition and phagocytosis of apoptotic cells.Nature,392 (6675), 505-509.