Demethylcantharidate (disodium)

Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer[1].

Product Specifications

CAS Number

[129-67-9]

UNSPSC

12352005

Hazard Statement

H301-H312-H315-H319-H335

Target

Apoptosis; Endogenous Metabolite

Type

Natural Products

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/demethylcantharidate-disodium.html

Purity

98.0

Solubility

H2O : 250 mg/mL (ultrasonic)

Smiles

O=C(C1C(C2OC1CC2)C(O[Na])=O)O[Na]

Molecular Formula

C8H8Na2O5

Molecular Weight

230.13

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Ye M, et al. Sodium demethylcantharidate induces apoptosis in hepatocellular carcinoma cells via ER stress. Am J Transl Res. 2019;11 (5) :3150-3158. Published 2019 May 15.