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CD83 Antibody [Michel17] (PE)

Product Specifications

Background

The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein. CD83 is expressed mainly on activated lymphocytes and mature dendritic cells and it plays a role in T cell development. The Michel-17 antibody does not induce an activation signal on dendritic or T cells.

NCBI Gene ID

12522

Swiss Prot

O88324

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

Michel17

Conjugation

PE

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=76-318

Fragment

Rat IgG1

Specificity

The Michel-17 monoclonal antibody specifically reacts with mouse CD83, a 45kDA type I transmembrane glycoprotein.

Symbol

Cd83

NCBI Official Name

CD83 antigen

NCBI Organism

Mus musculus

Background Reference 01

Cramer, S. O., Trumpfheller, C., Mehlhoop, U., Mor, S., Fleischer, B., von Bonin, A. (2000) . Activation-induced expression of murine CD83 on T cells and identification of a specific CD83 ligand on murine B cells.International immunology,12 (9), 1347-1351.

Background Reference 02

Wolenski, M., Cramer, S. O., Ehrlich, S., Steeg, C., Fleischer, B., Von Bonin, A. (2003) . Enhanced Activation of CD83‐Positive T Cells*.Scandinavian journal of immunology,58 (3), 306-311.

Background Reference 03

Breloer, M., Fleischer, B. (2008) . CD83 regulates lymphocyte maturation, activation and homeostasis.Trends in immunology,29 (4), 186-194.

Other Product Names

Cd83, Cd83

Tested Applications

Flow

Physical Properties

Liquid

Curated Selection

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