CD83 Antibody [HB15e] (FITC)

Product Specifications

Background

The HB15e monoclonal antibody specifically reacts with human CD83, a 43kDA single chain type I glycoprotein also known as HB15. A useful marker for mature human dendritic cells, it is also expressed on some activated lymphocytes. CD83’s precise role has not been deduced, but it is thought to be involved in antigen presentation.

NCBI Gene ID

9308

Swiss Prot

Q01151

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HB15e

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HB15e monoclonal antibody specifically reacts with human CD83, a 43kDA single chain type I glycoprotein also known as HB15.

Symbol

CD83

NCBI Official Name

CD83 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 02

Zhou, L. J., Schwarting, R., Smith, H. M., Tedder, T. F. (1992) . A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily.The Journal of Immunology,149 (2), 735-742.

Background Reference 03

Zhou, L. J., Tedder, T. F. (1995) . Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.The Journal of Immunology,154 (8), 3821-3835.