What is the catalog number for CD73 Antibody [AD2] (APC)?

The catalog number for CD73 Antibody [AD2] (APC) is 76-311.

What sizes are available for CD73 Antibody [AD2] (APC)?

CD73 Antibody [AD2] (APC) is available in the following size(s): 100 Tests.

Is CD73 Antibody [AD2] (APC) in stock?

CD73 Antibody [AD2] (APC) is currently made to order / not held in immediate stock. Contact us for lead time.

CD73 Antibody [AD2] (APC)

Product Specifications

Background

The AD2 monoclonal antibody specifically reacts with human CD73 (ecto-5’-nucleotidase), a 70 kDA glycosyl phosphatidylinositol (GPI) -anchored glycoprotein. CD73 catalyzes the dephosphorylation of adenosine monophosphate (AMP) to adenosine and is expressed on subsets of B, T, dendritic, endothelial, and mesenchymal stem cells. It is also involved in the adhesion of lymphocytes to endothelium and T cell activation.

NCBI Gene ID

4907

Swiss Prot

P21589

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

AD2

Conjugation

APC

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The AD2 monoclonal antibody specifically reacts with human CD73 (ecto-5’-nucleotidase), a 70 kDA glycosyl phosphatidylinositol (GPI) -anchored glycoprotein.

Symbol

NT5E

NCBI Official Name

5'-nucleotidase, ecto (CD73)

NCBI Organism

Homo sapiens

Background Reference 01

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 02

Nakamura, T., Kubagawa, H., Ohno, T., Cooper, M. D. (1993) . Characterization of an IgM Fc-binding receptor on human T cells.The Journal of Immunology,151 (12), 6933-6941.

Background Reference 03

Alam, M. S., Kurtz, C. C., Rowlett, R. M., Reuter, B. K., Wiznerowicz, E., Das, S., ... Ernst, P. B. (2009) . CD73 is expressed by human regulatory T helper cells and suppresses proinflammatory cytokine production and Helicobacter felis-induced gastritis in mice.Journal of Infectious Diseases,199 (4), 494-504.