CD33 Antibody [WM53] (FITC)

Product Specifications

Background

The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67. CD33 is expressed on monocytes, granulocytes, dendritic cells, mast cells, and myeloid progenitors to the exclusion of hematopoietic stem cells, lymphocytes, and platelets. It functions to assist sialic acid-dependent cell adhesion.

NCBI Gene ID

945

Swiss Prot

P20138

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

WM53

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Other

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The WM53 monoclonal antibody specifically reacts with human CD33, a 67 kDA transmembrane glycoprotein also known as GP67 and P67.

Symbol

CD33

NCBI Official Name

CD33 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 02

Favaloro, E. J., Bradstock, K. F., Kabral, A., Grimsley, P., Zowtyj, H., Zola, H. (1988) . Further characterization of human myeloid antigens (gp160, 95; gp150; gp67) : investigation of epitopic heterogeneity and non‐haemopoietic distribution using panels of monoclonal antibodies belonging to CD‐11b, CD‐13 and CD‐33.British journal of haematology,69 (2), 163-171

Background Reference 03

Freeman, S. D., Kelm, S., Barber, E. K., Crocker, P. R. (1995) . Characterization of CD33 as a new member of the sialoadhesin family of cellular interaction molecules.Blood,85 (8), 2005-2012.