What is the catalog number for CD3 Antibody [G4.18] (PE)?

The catalog number for CD3 Antibody [G4.18] (PE) is 76-239.

What sizes are available for CD3 Antibody [G4.18] (PE)?

CD3 Antibody [G4.18] (PE) is available in the following size(s): 0.1 mg.

Is CD3 Antibody [G4.18] (PE) in stock?

CD3 Antibody [G4.18] (PE) is currently made to order / not held in immediate stock. Contact us for lead time.

CD3 Antibody [G4.18] (PE)

Product Specifications

Background

The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR) . CD3 is involved in antigen recognition, cell activation, and signal transduction and is found on subsets of NK-T, peripheral T, dendritic epidermal T, and thymocyte cells. Immobilized G4.18 antibody activates T cells in vitro and in vivo treatments of the G4.18 antibody prevents cardiac and skin allograft rejection.

NCBI Gene ID

25710

Swiss Prot

P19377

Host

Mouse

Reactivity

Rat

Clonality

Monoclonal

Clone

G4.18

Conjugation

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG3, kappa

Specificity

The G4.18 monoclonal antibody specifically reacts with rat CD3, a T cell lineage marker and associated with the T cell receptor (TCR) .

Symbol

Cd3d

NCBI Official Name

CD3 molecule, delta

NCBI Organism

Rattus norvegicus

Background Reference 01

Nicolls, M. R., Aversa, G. G., Pearce, N. W., Spinelli, A., Berger, M. F., Gurley, K. E., Hall, B. M. (1993) . Induction of long-term specific tolerance to allografts in rats by therapy with an anti-CD3-like monoclonal antibody.Transplantation,55 (3), 459-468.

Background Reference 02

Morris, D. L., Komocsar, W. J. (1997) . Immunophenotyping analysis of peripheral blood, splenic, and thymic lymphocytes in male and female rats.Journal of pharmacological and toxicological methods,37 (1), 37-46.

Background Reference 03

Tran, G. T., Carter, N., He, X. Y., Spicer, T. S., Plain, K. M., Nicolls, M., ... Hodgkinson, S. J. (2001) . Reversal of experimental allergic encephalomyelitis with non-mitogenic, non-depleting anti-CD3 mAb therapy with a preferential effect on Th1 cells that is augmented by IL-4.International immunology,13 (9), 1109-1120.