CD81 Antibody [EAT-2 (Eat2) ]

Product Specifications

Background

The Eat-2 monoclonal antibody reacts with mouse CD81, a 26kDA non-glycosylated transmembrane protein. CD81 is expressed broadly on B cells, T cells, NK cells, dendritic cells, fibroblasts, and endothelial cells. It plays a role in T cell development and is involved in B and T cell adhesion. The Eat-2 antibody is also reported to cross-react with the rat CD81 antigen.

NCBI Gene ID

12520

Swiss Prot

P35762

Host

Hamster

Reactivity

Mouse

Clonality

Monoclonal

Clone

EAT-2 (Eat2)

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Armenian Hamster IgG

Specificity

The Eat-2 monoclonal antibody reacts with mouse CD81, a 26kDA non-glycosylated transmembrane protein.

Symbol

Cd81

NCBI Official Name

CD81 antigen

NCBI Organism

Mus musculus

Background Reference 01

Miyazaki, T., M, U., Campbell, K. S. (1997) . Normal development but differentially altered proliferative responses of lymphocytes in mice lacking CD81.The EMBO journal,16 (14), 4217-4225.

Background Reference 02

Boismenu, R., Rhein, M., Fischer, W. H., Havran, W. L. (1996) . A role for CD81 in early T cell development.Science,271 (5246), 198-200.

Background Reference 03

Maecker, H. T., Todd, S. C., Kim, E. C., Levy, S. (2000) . Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies.Hybridoma,19 (1), 15-22.