CD41a Antibody [HIP8] (PE)

Product Specifications

Background

The HIP8 monoclonal antibody specifically reacts with human CD41 (GPIIb), a subunit of the calcium-dependent complex with CD61 (IIIa) . The complex is expressed on megakaryocytes and platelets. The HIP8 antibody blocks the aggregation of platelets and inhibits platelet activation.

NCBI Gene ID

3674

Swiss Prot

P08514

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HIP8

Conjugation

Type

Primary Antibodies

Field of Research

Other

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HIP8 monoclonal antibody specifically reacts with human CD41 (GPIIb), a subunit of the calcium-dependent complex with CD61 (IIIa) .

Symbol

ITGA2B

NCBI Official Name

Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

NCBI Organism

Homo sapiens

Background Reference 01

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 02

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.