CD1d Antibody [1B1]
Product Specifications
Background
The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules. CD1d is expressed by mouse leukocytes, epithelial cells, thymocytes, and dendritic cells and is the only molecules in the CD1 family to have been found in the mouse. The 1B1 antibody detects CD1d in association with the Beta2m molecule.
NCBI Gene ID
12479
Swiss Prot
P11609
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Clone
1B1
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Innate Immunity
Purification
The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Concentration
Batch dependent
Buffer
Phosphate-buffered aqueous solution, ph7.2.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
The product should be stored undiluted at 4˚ C . Do not freeze.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=76-085
Fragment
Rat IgG2b, kappa
Specificity
The 1B1 monoclonal antibody specifically reacts with mouse CD1d, a 48kDA type I membrane glycoprotein with a structural homology to MHC class I molecules.
Symbol
Cd1d1
NCBI Official Name
CD1d1 antigen
NCBI Organism
Mus musculus
Background Reference 01
Szalay, G., Ladel, C. H., Blum, C., Brossay, L., Kronenberg, M., Kaufmann, S. H. (1999) . Cutting edge: anti-CD1 monoclonal antibody treatment reverses the production patterns of TGF--beta-2 and Th1 cytokines and ameliorates listeriosis in mice.The Journal of Immunology,162 (12), 6955-6958.
Background Reference 02
Roark, J. H., Park, S. H., Jayawardena, J., Kavita, U., Shannon, M., Bendelac, A. (1998) . CD1. 1 expression by mouse antigen-presenting cells and marginal zone B cells.The Journal of Immunology,160 (7), 3121-3127.
Background Reference 03
Amano, M., Baumgarth, N., Dick, M. D., Brossay, L., Kronenberg, M., Herzenberg, L. A., Strober, S. (1998) . CD1 expression defines subsets of follicular and marginal zone B cells in the spleen: -beta-2-microglobulin-dependent and independent forms.The Journal of Immunology,161 (4), 1710-1717.
Other Product Names
Cd1a, Cd1d, CD1.1, Ly-38, AI747460, Cd1d1
Tested Applications
Flow, Functional Assays
Physical Properties
Liquid
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