CD1a Antibody [HI149] (FITC)

Product Specifications

Background

The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein. It is expressed on dendritic cells, Langerhans cells, and cortical thymocytes. CD1a plays a role in antigen presentation and , like MHC Class I, it non-covalently associates with Beta2-microglobulin.

NCBI Gene ID

909

Swiss Prot

P06126

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

HI149

Conjugation

FITC

Type

Primary Antibodies

Field of Research

Innate Immunity, Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The HI149 monoclonal antibody specifically reacts with human CD1a, a 49kDA type I membrane glycoprotein.

Symbol

CD1A

NCBI Official Name

CD1a molecule

NCBI Organism

Homo sapiens

Background Reference 01

Leucocyte typing IV: white cell differentiation antigens. Oxford University Press, 1989.

Background Reference 02

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 03

Hanau, D., Schmitt, D. A., Bieber, T., Schmitt, D., Cazenave, J. P. (1990) . Possible mechanism of action of CD1a antigens.Journal of investigative dermatology,95 (5), 503-505.