CD90 Antibody [G7]

Product Specifications

Background

The G7 monoclonal antibody specifically reacts with mouse CD90, also known as thymus cell antigen-1 (Thy-1) . CD90 is a 25-35 kDA GPI-anchored protein is the smallest member of the Ig superfamily. CD90 is expressed on thymocytes, neurons, hematopoietic stem cells, and T cells. It plays a role in T cell signal transduction and adhesion. The G7 antibody is reported to stimulate IL-2 secretion and T cell proliferation.

NCBI Gene ID

21838

Swiss Prot

P01831

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Rat IgG2c, kappa

Specificity

The G7 monoclonal antibody specifically reacts with mouse CD90, also known as thymus cell antigen-1 (Thy-1) .

Symbol

Thy1

NCBI Official Name

Thymus cell antigen 1, theta

NCBI Organism

Mus musculus

Background Reference 01

Kruisbeek, A. M., Shevach, E., Thornton, A. M. (2004) . Proliferative assays for T cell function.Current protocols in immunology, 3-12.

Background Reference 02

Nitta, H., Munger, W., Wilson, E., Ralston, R., Alila, H. (1997) . Improved in situ immunodetection of leukocytes on paraffin-embedded mouse spleen.Cell Vision,4, 74-80.

Background Reference 03

Gunter, K. C., Malek, T. R., Shevach, E. M. (1984) . T cell-activating properties of an anti-Thy-1 monoclonal antibody. Possible analogy to OKT3/Leu-4.The Journal of experimental medicine,159 (3), 716-730.