What is the catalog number for CD90.2 Antibody [30-H12] (Violet-450)?

The catalog number for CD90.2 Antibody [30-H12] (Violet-450) is 76-070.

What sizes are available for CD90.2 Antibody [30-H12] (Violet-450)?

CD90.2 Antibody [30-H12] (Violet-450) is available in the following size(s): 0.1 mg.

Is CD90.2 Antibody [30-H12] (Violet-450) in stock?

CD90.2 Antibody [30-H12] (Violet-450) is currently made to order / not held in immediate stock. Contact us for lead time.

CD90.2 Antibody [30-H12] (Violet-450)

Product Specifications

Background

The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.2, expressed on thymocytes, mature T cells, epithelial cells, neurons, hematopoietic stem cells, and fibroblasts. CD90 is a membrane glycoprotein that regulates the adhesion and signal transduction in T lymphocytes, and the adhesion of thymocytes to thymic stroma. The interaction between 30-H12 and the antibody to the CD3/TCR complex upregulates thymocytes signal transduction and apoptosis and downregulates mature T cell proliferation. The 30-H12 antibody seems to be unable to cross-link with CD90.1.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.

NCBI Gene ID

21838

Swiss Prot

P01831

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

30-H12

Conjugation

Violet-450

Type

Primary Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Rat IgG2b

Specificity

The 30-H12 monoclonal antibody specifically binds to MouseCD90.2, an alloantigen known as Thy-1.

Symbol

Thy1

NCBI Official Name

Thymus cell antigen 1, theta

NCBI Organism

Mus musculus

Background Reference 01

Ledbetter, J. A., Herzenberg, L. A. (1979) . Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*.Immunological reviews,47 (1), 63-90.

Background Reference 02

Radrizzani, M., Carminatti, H., Pivetta, O. H., Vargas, V. P. (1995) . Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum.Journal of neuroscience research,42 (2), 220-227.

Background Reference 03

Seaman, W. E., Wofsy, D., Greenspan, J. S., Ledbetter, J. A. (1983) . Treatment of autoimmune MRL/Ipr mice with monoclonal antibody to Thy-1.2: a single injection has sustained effects on lymphoproliferation and renal disease.The Journal of Immunology,130 (4), 1713-1718.