CD90 Antibody [5E10] (PE)

Product Specifications

Background

The 5E10 monoclonal antibody specifically reacts with human CD90, also known as thymus cell antigen-1 (Thy-1) . CD90 is a 25-37 kDA GPI-anchored protein is the smallest member of the Ig superfamily. CD90 is expressed on thymocytes, neurons, mesenchymal stem cells, hematopoietic stem cells, NK cells, and follicular dendritic cells and plays a role in inflammation, metastasis, apoptosis, and nerve regeneration. The 5E10 antibody can be used for the enriching high proliferative potential colony-forming cells (HIPP-CFC) .

NCBI Gene ID

7070

Swiss Prot

P04216

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

5E10

Conjugation

Type

Primary Antibodies

Field of Research

Immunology, Stem Cell

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG1, kappa

Specificity

The 5E10 monoclonal antibody specifically reacts with human CD90, also known as thymus cell antigen-1 (Thy-1) .

Symbol

THY1

NCBI Official Name

Thy-1 cell surface antigen

NCBI Organism

Homo sapiens

Background Reference 01

Craig, W., Kay, R., Cutler, R. L., Lansdorp, P. M. (1993) . Expression of Thy-1 on human hematopoietic progenitor cells.The Journal of experimental medicine,177 (5), 1331-1342.

Background Reference 02

Trickett, A. E., Ford, D. J., Lam-Po-Tang, P. R., Vowels, M. R. (1991) . Immunomagnetic bone marrow purging of common acute lymphoblastic leukemia cells: suitability of BioMag particles.Bone marrow transplantation,7 (3), 199-203.

Background Reference 03

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.