What is the catalog number for CD20 Antibody [AISB12]?

The catalog number for CD20 Antibody [AISB12] is 76-010.

What sizes are available for CD20 Antibody [AISB12]?

CD20 Antibody [AISB12] is available in the following size(s): 0.1 mg.

Is CD20 Antibody [AISB12] in stock?

CD20 Antibody [AISB12] is currently made to order / not held in immediate stock. Contact us for lead time.

CD20 Antibody [AISB12]

Product Specifications

Background

The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule. CD20 is expressed by B cells in all stage of development, except for the initial pro-B and final plasma cells. CD20 has no natural ligands and has an important role in enabling B cells to respond optimally to T-independent antigens. The AISB12 antibody binds to the extracellular loop domain of the CD20 molecule.

NCBI Gene ID

12482

Swiss Prot

P19437

Host

Rat

Reactivity

Mouse

Clonality

Monoclonal

Clone

AISB12

Conjugation

Unconjugated

Type

Primary Antibodies, Functional Antibodies

Field of Research

Immunology

Purification

The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C . Do not freeze.

Fragment

Rat IgG2a

Specificity

The AISB12 monoclonal antibody specifically reacts with mouse cd20, a 32kDA B-lymphocyte surface molecule.

Symbol

Ms4a1

NCBI Official Name

Membrane-spanning 4-domains, subfamily A, member 1

NCBI Organism

Mus musculus

Background Reference 01

Uchida, J., Hamaguchi, Y., Oliver, J. A., Ravetch, J. V., Poe, J. C., Haas, K. M., Tedder, T. F. (2004) . The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptordependent mechanisms during anti-CD20 antibody immunotherapy.The Journal of experimental medicine,199 (12), 1659-1669.

Background Reference 02

Uchida, J., Lee, Y., Hasegawa, M., Liang, Y., Bradney, A., Oliver, J. A., ... Tedder, T. F. (2004) . Mouse CD20 expression and function.International immunology,16 (1), 119-129.

Background Reference 03

Qian, J., Zheng, Y., Zheng, C., Wang, L., Qin, H., Hong, S., ... Yi, Q. (2012) . Active vaccination with Dickkopf-1 induces protective and therapeutic antitumor immunity in murine multiple myeloma.Blood,119 (1), 161-169.