CD10 Antibody [CB-CALLA] (APC)

Product Specifications

Background

The CB-CALLA monoclonal antibody specifically reacts with human CD10, a 100kDA type II glycoprotein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on neutrophils and the precursors of B and T cells. It is involved in the neutrophil inflammatory and chemotactic responses and B cell development.

NCBI Gene ID

4311

Swiss Prot

P08473

Host

Mouse

Reactivity

Human

Clonality

Monoclonal

Clone

CB-CALLA

Conjugation

APC

Type

Primary Antibodies

Field of Research

Innate Immunity

Purification

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Concentration

Batch dependent

Buffer

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Fragment

Mouse IgG2b, kappa

Specificity

The CB-CALLA monoclonal antibody specifically reacts with human CD10, a 100kDA type II glycoprotein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin.

Symbol

MME

NCBI Official Name

Membrane metallo-endopeptidase

NCBI Organism

Homo sapiens

Background Reference 01

Schlossman, S. F. (1995) .Leucocyte typing V: White cell differentiation antigens: Proceedings of the Fifth International Workshop and Conference, Held in Boston, USA 3-7 November, 1993. Oxford University Press.

Background Reference 02

Ritz, J., Pesando, J. M., Notis-McConarty, J., Lazarus, H., Schlossman, S. F. (1980) . A monoclonal antibody to human acute lymphoblastic leukaemia antigen.

Background Reference 03

McCormack, R. T., Nelson, R. D., LeBien, T. W. (1986) . Structure/function studies of the common acute lymphoblastic leukemia antigen (CALLA/CD10) expressed on human neutrophils.The Journal of Immunology,137 (3), 1075-1082.