P90RSK (phospho Ser352) Antibody

Product Specifications

Background

Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.

NCBI Gene ID

6195

Swiss Prot

Q15418

Accession Number

NP_001006666.1

Host

Rabbit

Reactivity

Human

Immunogen

P90RSK (Phospho-Ser352) antibody was raised against a peptide sequence around phosphorylation site of serine 352 (R-D-S (p) -P-G) derived from Human p90RSK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific, Apoptosis, Cancer, Cell Cycle

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

90 kDa

Specificity

This antibody detects endogenous level of p90RSK only when phosphorylated at serine 352.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

RPS6KA1

NCBI Official Name

Ribosomal protein S6 kinase, 90kDa, polypeptide 1

NCBI Organism

Homo sapiens

Background Reference 01

Silverman E, et al. Mol Cell Biol. 2004 Dec; 24 (24) : 10573-10583. Itoh S, et al. J Biol Chem 2005 Jun 24; 280 (25) : 24135-24142Eisenmann KM, et al. Cancer Res 2003 Dec 01; 63 (23) : 8330-7