PLCgamma1 (phospho Tyr783) Antibody

Product Specifications

Background

PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor) -activated tyrosine kinase.

NCBI Gene ID

5335

Swiss Prot

P19174

Accession Number

NP_002651.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PLCgamma1 (Phospho-Tyr783) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 783 (G-F-Y (p) -V-E) derived from Human PLCG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific, Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

155 kDa

Specificity

This antibody detects endogenous level of PLCγ1 only when phosphorylated at tyrosine 783.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

PLCG1

NCBI Official Name

Phospholipase C, gamma 1

NCBI Organism

Homo sapiens

Background Reference 01

DeBell KE, et al. Mol Cell Biol. 1999 Nov; 19 (11) : 7388-7398. Verí MC, et al. Mol Cell Biol. 2001 Oct; 21 (20) : 6939-6950. Sette C, et al. EMBO J. 2002 Oct 15; 21 (20) : 5386-5395.