PKD / PKCmu (phospho Ser738) Antibody
Product Specifications
Background
Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-κ -B.
NCBI Gene ID
5587
Swiss Prot
Q15139
Accession Number
NP_002733.2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
PKD/PKCmu (Phospho-Ser738) antibody was raised against a peptide sequence around phosphorylation site of serine 738 (E-K-S (p) -F-R) derived from Human PKD/PKCμ .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Phospho-Specific, Apoptosis, Cancer, Neuroscience
Purification
Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
Phospho-Specific
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
115 kDa
Specificity
This antibody detects endogenous level of PKD/PKCmu only when phosphorylated at serine 738.
Applications Notes
Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Symbol
PRKD1
NCBI Official Name
Protein kinase D1
NCBI Organism
Homo sapiens
Background Reference 01
Storz P, et al. Mol Cell Biol. 2004 Apr; 24 (7) : 2614-2626. Storz P, et al. Mol Cell Biol. 2005 Oct; 25 (19) : 8520-8530. Zhang W, et al. J Biol Chem 2005 May 13; 280 (19) : 19036-19044
Other Product Names
PKD, PKCM, PRKCM, PKC-MU, VASA, KPCD1, PKC-mu, PKD
Tested Applications
WB, IF
Protein ID
115529463
Physical Properties
Liquid
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