PKD / PKCmu (phospho Ser738) Antibody

Product Specifications

Background

Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-κ -B.

NCBI Gene ID

5587

Swiss Prot

Q15139

Accession Number

NP_002733.2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PKD/PKCmu (Phospho-Ser738) antibody was raised against a peptide sequence around phosphorylation site of serine 738 (E-K-S (p) -F-R) derived from Human PKD/PKCμ .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific, Apoptosis, Cancer, Neuroscience

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

115 kDa

Specificity

This antibody detects endogenous level of PKD/PKCmu only when phosphorylated at serine 738.

Applications Notes

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

Symbol

PRKD1

NCBI Official Name

Protein kinase D1

NCBI Organism

Homo sapiens

Background Reference 01

Storz P, et al. Mol Cell Biol. 2004 Apr; 24 (7) : 2614-2626. Storz P, et al. Mol Cell Biol. 2005 Oct; 25 (19) : 8520-8530. Zhang W, et al. J Biol Chem 2005 May 13; 280 (19) : 19036-19044