What is the catalog number for FAK (phospho Tyr861) Antibody?

The catalog number for FAK (phospho Tyr861) Antibody is 79-441.

What sizes are available for FAK (phospho Tyr861) Antibody?

FAK (phospho Tyr861) Antibody is available in the following size(s): 0.1 mg.

Is FAK (phospho Tyr861) Antibody in stock?

FAK (phospho Tyr861) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

FAK (phospho Tyr861) Antibody

Product Specifications

Background

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

NCBI Gene ID

5747

Swiss Prot

Q05397

Accession Number

NP_005598.3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

FAK (Phospho-Tyr861) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 861 (H-I-Y (p) -Q-P) derived from Human FAK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Phospho-Specific

Purification

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Concentration

1 mg/mL

Buffer

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Modification

Phospho-Specific

Shipping Conditions

Blue Ice

Storage Conditions

Store antibody at -20˚ C for up to one year.

Calculated Molecular Weight

125 kDa

Specificity

This antibody detects endogenous level of FAK only when phosphorylated at tyrosine 861.

Applications Notes

Western Blot: 1:500~1:1000

Symbol

PTK2

NCBI Official Name

Protein tyrosine kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Shi Q, et al. (2003) Mol Biol Cell; 14 (10) : 4306-15. Vadlamudi RK, et al. (2003) FEBS Lett; 543 (1-3) : 76-80. Eliceiri BP, et al. (2002) J Cell Biol Apr 01; 157 (1) : 149-60. Abu-Ghazaleh R, (2001) et al. Biochem J; 360 (Pt 1) : 255-64.